Pharmacological properites:

  Dexamethasone is a very potent synthetic glucocorticosteroid, its anti-inflammatory effects being 30 times stronger than those of cortisone and 7-10 times stronger than those of pridnisolone. In addition to its antiphlogistic properties, dexamethasone also shows extraordinary anti-allergic, anti-stress and gluconeogenetic activities.  Mineralcorticoid activity is minimal.

 

Indication:

 

Metabolic disorders such as: ketosis in cattle and puerperal toxaemia in ewes and sows.

Non-infectious inflammatory processes, especially acute musculoskeletal inflammations such as: arthritis, periarthritis, tendovaginitis, bursitis, luxations, myositis, osselets and sprains.

As an aid in acute infectious diseases (e.g. acute mastitis, metritis, pneumonia, polyarthritis in calves) in combination with suitable anti-infectious therapy.

allergic conditions, e.g. asthma, allergic skin affections (eczema, urticaria,pruritis, ), laminitis in horses and cattle, snake-bites.

Stress-and shock conditions

Induction of parturition in ruminants during the last stage of pregnancy ( delivery within 2-4 days).

 

Dosage and administration:

By intravenous, intramuscular or subcutaneous (dogs, cats) injection:

 

Cats, dogs:	(0.1-0.2 mg/kg b.w.)   0.25-0.5 ml/5 kg
Cattle, horses:	(2.5-5 mg/100 kg b.w.)  5-10 ml/400 kg
Sheep, goats, calves:	(2-4 mg/50 kg )   1-2 ml/50 kg

 

If necessary repeat with 2 days intervals in dogs and cats and 3-4 days intervals in other animals.

 

--For induction of parturition in cows (given within 1 week before expected calving date): (5 mg/100 kg b.w.)  2.5 ml/100kg

--Puerperal toxaemia and induction of parturition in sheep and goats: (2.5 mg/10 kg b.w.)  6 ml/50 kg

--Shock-therapy: by slow I.V. injection of high doses(10*), eventually to be repeated after 8-12h.

 

By intraarticular injection: according to the extension of joint and animal weight: 0.25 to 4 ml.