Hypersensitivity to diminazene or phenazone.
Administration to animals with an impaired renal and / or hepatic function.

Hypersensitivity reactions.
Salivation, sweating, tremors can occur.
Multiple therapeutic doses can produce severe nervous signs and prominent haemorrhagic and malacic lesions of the cerebellum, midbrain, and thalamus in dogs.
After multiple therapeutic doses degenerative fatty changes can occur in liver, kidneys, myocardium and muscles.
Multiple therapeutic doses can produce prominent haemorrhagic and malacic lesions of the cerebellum and the thalamus in cattle.