The cause of disease, the disease is a zoonosis of acute, traumatic, toxic infectious disease. The pathogen is Clostridium Clostridium tetani. It is usually caused by an infection of the wound with a substance containing Clostridium tetani spores. When the wound is small and deep, necrosis occurs in the wound or the wound is covered by soil, feces, scab, etc. . The tissue in the wound is seriously damaged, bleeding, foreign body, or in the case of mixed infection with aerobic bacteria, the Clostridium tetani can grow, produce toxins, and cause disease. Sheep are often infected by skin trauma, castration, ewe delivery, and improper handling of the fetus.

Symptoms, incubation period generally 5-15 days. The initial symptoms are not obvious, often manifested as stiffness of the limbs, lack of energy, general dullness, dyskinesia, angular arch inversion (especially when lying down) , closed teeth, drooling, and difficulty eating, and often occurs mild distension. A sudden noise can cause muscle spasms that cause sick sheep to fall to the ground. In the late stage of the disease, death was caused by asphyxia, especially in lambs.

Prevention and CURE method, tetanus toxoid can better prevent this disease. For the prevention of lambs, it is more suitable to inject tetanus toxoid in the late pregnancy of ewes. Wound management: effective antiseptic treatment of infected wounds, the complete discharge of pus, foreign bodies, necrotic tissue and scab, and disinfection of the wound with disinfectant solution. In addition, penicillin and streptomycin were injected around the wound to eliminate the source of tetanus toxin. At the same time in Lambs Cut Umbilical, male castration, Ewe should pay attention to the delivery of instruments, surgical site disinfection. Early use of tetanus serum (tetanus antitoxin) , can use a sufficient amount (200-800,000 units) , but also the total amount of 2-3 injections. Subcutaneous, muscle, intravenous injection can be, or half subcutaneous or muscle injection, half intravenous injection.