Sofosbuvir is first without joint interferon can be safe and effective drug for the treatment of certain types of hepatitis c.Clinical trials confirm for type 1 and 4 c, the drug combination of polyethylene glycol (peg) interferon and ribavirin overall sustained virological response (SVR) is as high as 90%;In view of the type 2 c, the drug plus ribavirin SVR is 89% - 95%;In view of the 3 c, the drug plus ribavirin SVR is 61% - 63%.